Chistolini P, De Angelis G, De Luca M, Pellegrini G, Ruspantini I
Biomedical Engineering, Lab., Istituto Superiore di Sanità, Rome, Italy.
Med Biol Eng Comput. 1999 Sep;37(5):670-2. doi: 10.1007/BF02513365.
Human epidermis can be reconstructed in vitro and is currently used in autografts for the treatment of severe, extensive burns and pigmentation disorders. However, there are neither international standards nor a common nomenclature for engineered tissues. The paper discusses the results of a preliminary study on human cultured epidermis to assess its mechanical tensile strength, and to eventually establish mechanical evaluation criteria that will enable test and comparison of the behaviour of different engineered tissue products. To perform uniaxial tension tests a traditional testing machine was adapted, and dedicated sample holding frame and grips designed.
人类表皮可以在体外重建,目前用于自体移植,治疗严重的大面积烧伤和色素沉着紊乱。然而,对于工程组织既没有国际标准,也没有通用的命名法。本文讨论了一项关于人类培养表皮的初步研究结果,以评估其机械拉伸强度,并最终建立机械评估标准,以便能够测试和比较不同工程组织产品的性能。为了进行单轴拉伸试验,对传统试验机进行了改装,并设计了专用的样品固定框架和夹具。