Hesse F, Wagner R
Cell Culture Technology Department, Gesellschaft für Biotechnologische Forschung mbH, 38124 Braunschweig, Germany.
Trends Biotechnol. 2000 Apr;18(4):173-80. doi: 10.1016/s0167-7799(99)01420-1.
During recent years, biopharmaceutical products manufactured by processes that use mammalian cell cultures have gained increasing importance. At the same time, a strong awareness of the importance of the safety and quality of such products has also emerged. This has led to improvements in cultivation and production technology, validation procedures and process organization.
近年来，采用哺乳动物细胞培养工艺生产的生物制药产品变得越来越重要。与此同时，人们也强烈意识到此类产品安全性和质量的重要性。这促使培养和生产技术、验证程序以及工艺组织都得到了改进。
