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Silencing of the Y-chromosomal gene tspy during murine evolution.

作者信息

Schubert S, Dechend F, Skawran B, Kunze B, Winking H, Weile C, Römer I, Hemberger M, Fundele R, Sharma T, Schmidtke J

机构信息

Institut für Humangenetik, Medizinische Hochschule, Hannover, Germany.

出版信息

Mamm Genome. 2000 Apr;11(4):288-91. doi: 10.1007/s003350010054.

DOI:10.1007/s003350010054
PMID:10754104
Abstract

We have studied the process of tspy gene silencing in murine evolution. We have isolated functional tspy sequences from Apodemus agrarius, A. sylvaticus, A. flavicollis, and Mus platythrix (subgenus Pyromys) and nonfunctional tspy sequences from species of the subgenus Mus. We present two alternative models as to how tspy may have lost its function in the murine lineage.

摘要

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