Davidson J R
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC 27710, USA.
J Clin Psychiatry. 2000;61 Suppl 5:52-6; discussion 57-9.
Posttraumatic stress disorder (PTSD) is a prevalent and disabling condition. Treatment is essential to reduce symptoms, increase the patient's functioning and well-being, and reduce comorbidity with other psychological disorders. Evidence suggests that psychopharmacologic therapy can be effective in PTSD. This article considers clinical data for various pharmacologic treatment options for PTSD; in particular, several recent studies of selective serotonin reuptake inhibitors are examined. The long-term effects of pharmacotherapy and issues concerning patient management are also discussed.
创伤后应激障碍（PTSD）是一种常见且致残的病症。治疗对于减轻症状、提高患者的功能水平和幸福感以及减少与其他心理障碍的共病情况至关重要。有证据表明，心理药物治疗对创伤后应激障碍可能有效。本文探讨了针对创伤后应激障碍的各种药物治疗选择的临床数据；特别是，对几项最近关于选择性5-羟色胺再摄取抑制剂的研究进行了审视。还讨论了药物治疗的长期效果以及与患者管理相关的问题。
