Bernard P, Vitrey D, Boursier C, Brunot J, Fléchaire A
Département de la clinique médicale, hôpital d'instruction des armées Desgenettes, Lyon, France.
Rev Med Interne. 2000 Mar;21(3):278-81. doi: 10.1016/s0248-8663(00)80047-8.
Olfactory esthesioneuroblastoma is an uncommon neuroectodermal tumor originating from the olfactory epithelium, which is rarely associated with hormone excess syndrome.
Asymptomatic olfactory esthesioneuroblastoma was diagnosed in a 22-year-old man who presented a syndrome of inappropriate antidiuretic hormone secretion. Following surgery, the immunohistochemical analysis demonstrated the existence of neurophysin hormone in tumoral cells.
This case provides evidence that olfactory esthesioneuroblastoma can be uncovered by inappropriate antidiuretic hormone secretion.
嗅神经母细胞瘤是一种罕见的起源于嗅上皮的神经外胚层肿瘤,很少与激素过多综合征相关。
一名22岁男性被诊断为无症状嗅神经母细胞瘤,该患者出现了抗利尿激素分泌异常综合征。手术后,免疫组织化学分析显示肿瘤细胞中存在神经垂体激素。
该病例证明嗅神经母细胞瘤可通过抗利尿激素分泌异常被发现。