Myers S L, Hardy D A, Wiebe C B, Shiffman J
Department of Diagnostic and Surgical Sciences, College of Dentistry, University of Saskatchewan, Saskatoon, Canada.
Oral Surg Oral Med Oral Pathol. 1994 Jun;77(6):645-50. doi: 10.1016/0030-4220(94)90328-x.
Olfactory neuroblastoma is an uncommon intranasal neoplasm that has not been previously documented to invade the oral cavity. The tumor's variable clinical manifestations and microscopic features may create a diagnostic dilemma for the clinician. The neoplasm has been identified as a direct cause of ectopic arginine vasopressin production leading to inappropriate antidiuretic hormone secretion. An unusual case of olfactory neuroblastoma invading the oral cavity through the maxillary sinus in a patient with pathologic antidiuretic hormone secretion is reported.
嗅神经母细胞瘤是一种罕见的鼻腔内肿瘤，此前尚无侵袭口腔的记录。该肿瘤多样的临床表现和微观特征可能给临床医生带来诊断难题。该肿瘤已被确认为异位精氨酸加压素产生导致抗利尿激素分泌异常的直接原因。本文报告了一例患有病理性抗利尿激素分泌的患者，其嗅神经母细胞瘤经上颌窦侵袭口腔的罕见病例。
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