[培养的人和动物细胞中的D型肿瘤病毒相关抗原]
[Oncornavirus D associated antigen in cultured human and animal cells].
作者信息
Posevaia T A, Kosiakova N P, Tsareva A A, Novokhatskiĭ A S
出版信息
Vopr Virusol. 1978 Nov-Dec(6):714-7.
A large number of long-term continuous (LTC) and primarily trypsinized (PT) human and animal cell cultures were examined for the presence of a new oncornavirus D-associated antigen. All the PT cultures were found to be free from this antigen as also human diploid cells and LTC cells of man, rabbit, mouse, dog, swine and bat. LTC cells of monkey, bull, and Syrian hamster, however, were found to contain oncornavirus D-associated antigen identical to that previously found in HeLa, HEp-2 and J-96 cells. The detection of oncornavirus D-associated antigen in cells may indicate their infection with this virus.
对大量长期连续培养（LTC）且主要经胰蛋白酶处理（PT）的人和动物细胞培养物进行检测，以确定是否存在一种与新的D型肿瘤病毒相关的抗原。结果发现，所有经胰蛋白酶处理的培养物以及人、兔、小鼠、狗、猪和蝙蝠的人二倍体细胞和长期连续培养细胞均未检测到这种抗原。然而，在猴、牛和叙利亚仓鼠的长期连续培养细胞中，发现含有与先前在HeLa、HEp - 2和J - 96细胞中发现的相同的与D型肿瘤病毒相关的抗原。在细胞中检测到与D型肿瘤病毒相关的抗原可能表明这些细胞已被该病毒感染。
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