[寻找人类乳腺癌肿瘤中与D型肿瘤病毒相关的新抗原]
[Search for a new antigen associated with oncornavirus D in human breast cancer tumors].
作者信息
Kosiakov P N, Korosteleva V S, Pavliuchenkova R P, Kosiakova N, Nabokov Iu S
出版信息
Vopr Virusol. 1979 May-Jun(3):247-51.
PMID:88817
Abstract
An antigen similar in its specificity to a nonvirion antigen emerging in stationary tissue culture cells spontaneously or experimentally infected with oncornavirus D was found in mammary gland cancer tumour tissues of 9 out of 54 examined patients. This virus-associated antigen was absent in 17 examined specimens of benign tumours of the same localization (fibroadenomas, mastopathies) or in the organs of a normal adult man or human embryo.
摘要
在54例接受检查的患者中，有9例乳腺癌肿瘤组织中发现了一种抗原，其特异性与在自发或经实验感染D型肿瘤病毒的静止组织培养细胞中出现的非病毒体抗原相似。在17例相同部位的良性肿瘤（纤维腺瘤、乳腺病）检查标本中，或在正常成年男性或人类胚胎的器官中，未发现这种病毒相关抗原。
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