Panagariya A, Jain R S, Sharma A K
Dept of Neurology, BMRC SMS Medical College Hospital, Jaipur.
J Assoc Physicians India. 1999 May;47(5):548-50.
Creutzfeldt-Jakob disease (CJD) is a degenerative process of the brain, induced by novel infectious agent or prion, and is usually characterized by a rapidly progressive dementia in association with myoclonus. However different patterns of disease presentation have been identified. The authors describe three probable cases of CJD. None of them had positive family history or any known modes of iatrogenic transmission. Interestingly, all the cases presented like a stroke. This is the first series of CJD cases from this part of country.
克雅氏病(CJD)是一种由新型传染因子或朊病毒引起的脑部退行性病变,通常表现为快速进展的痴呆并伴有肌阵挛。然而,已经发现了不同的疾病表现形式。作者描述了三例可能的克雅氏病病例。他们均无阳性家族史或任何已知的医源性传播途径。有趣的是,所有病例均表现为类似中风的症状。这是该国该地区的首例克雅氏病病例系列报道。