Jansen T, Romiti R, Plewig G, Altmeyer P
Department of Dermatology, Ruhr-University, Bochum, Germany.
Pediatr Dermatol. 2000 Mar-Apr;17(2):123-5. doi: 10.1046/j.1525-1470.2000.01728.x.
A 17-year-old girl with a 9-month history of papulopustular acne developed disfiguring, highly inflammatory, fluctuant nodules in both nasolabial folds within 2 months. Periodically she experienced discharge of pus and blood from these lesions. A diagnosis of disfiguring draining sinus tracts associated with acne vulgaris was made. The therapeutic regimen included intralesional corticosteroid injection, systemic corticosteroids along with a macrolide antibiotic, and systemic isotretinoin to reduce the inflammatory process. Outcome was favorable, with no recurrences during the following 10 months. Draining sinus is a malevolent lesion usually seen in severe forms of acne such as acne conglobata, acne fulminans, and acne inversa. Treatment is difficult and often unsatisfactory. In many cases, excision of the lesion is necessary to provide a permanent cure.
一名患有丘疹脓疱性痤疮9个月的17岁女孩在2个月内双侧鼻唇沟出现毁容性、高度炎症性、波动性结节。这些皮损不时有脓血排出。诊断为与寻常痤疮相关的毁容性引流窦道。治疗方案包括皮损内注射皮质类固醇、全身性皮质类固醇联合大环内酯类抗生素以及全身性异维A酸以减轻炎症过程。结果良好,在接下来的10个月内无复发。引流窦是一种严重的皮损,通常见于聚合性痤疮、暴发性痤疮和反向性痤疮等严重形式的痤疮。治疗困难且往往不尽人意。在许多情况下,需要切除皮损才能实现永久治愈。