Liddicoat J E, Bekassy S M, Beall A C, Glaeser D H, DeBakey M E
Ann Surg. 1975 May;181(5):747-53. doi: 10.1097/00000658-197505000-00033.
Numerous studies have demonstrated the superiority of membrane oxygenators (MO) over the bubble oxygenators (BO) when used for prolonged cardiopulmonary support. However, there is little information available evaluating the MO for routine, short-term cardiopulmonary bypass. In this study the 5MO314 Modulung-Teflo (MO) was compared to 5M30314 Miniprime Variflo (BO). The data of 91 patients (46 MO and 45 BO) were analyzed according to the duration of cardiopulmonary bypass (Group I less than 60 min., Group II 60-90 min. and Group III greater than 90 min.). Hemodynamic parameters, fluid and blood balance, as well as hematologic and blood gas studies were used for comparing the two oxygentors. The hemodynamic parameters were better, and the arterial blood gases were more physilogic with the MO. The postoperative blood loss was significantly less when using the MO. The other measurements documented the stability of the MO. All statements were based on statistical analysis with a DEC PDP-9 computer, using the MIIS language and operating system. Consequently, we are now using this MO for routine cardiopulmonary bypass.
众多研究表明，在用于长时间心肺支持时，膜式氧合器（MO）优于鼓泡式氧合器（BO）。然而，关于MO用于常规短期体外循环的评估信息却很少。在本研究中，将5MO314 Modulung - Teflo（MO）与5M30314 Miniprime Variflo（BO）进行了比较。根据体外循环持续时间（I组小于60分钟，II组60 - 90分钟，III组大于90分钟）对91例患者（46例使用MO，45例使用BO）的数据进行了分析。使用血流动力学参数、液体和血液平衡以及血液学和血气研究来比较这两种氧合器。使用MO时，血流动力学参数更好，动脉血气更符合生理状态。使用MO时术后失血量明显更少。其他测量结果证明了MO的稳定性。所有陈述均基于使用DEC PDP - 9计算机、MIIS语言和操作系统进行的统计分析。因此，我们现在在常规体外循环中使用这种MO。
