Hofmeyr G J
Department of Obstetrics and Gynaecology, Coronation Hospital and University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa.
Cochrane Database Syst Rev. 2000(2):CD000136. doi: 10.1002/14651858.CD000136.
Maternal oxygen administration has been used in an attempt to lessen fetal distress by increasing the available oxygen from the mother.
The objective of this review was to assess the effects of maternal oxygenation for fetal distress during labour and to assess the effects of prophylactic oxygen therapy during the second stage of labour on perinatal outcome.
The Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register were searched. Date of last search: December 1997.
Randomised trials comparing maternal oxygen therapy for fetal distress during labour and prophylactic oxygen therapy during the second stage of labour with a control group (dummy or no oxygen therapy).
Eligibility and trial quality were assessed by the reviewer.
No trials addressing maternal oxygen therapy for fetal distress could be located. One trial of 85 women which addressed prophylactic oxygen therapy during labour was included. Cord blood pH values of less than 7.2 were more frequently recorded in the oxygenation group than the control group (relative risk 4.83, 95% confidence interval 1.11 to 21.04). There were no other statistically significant differences between the groups. Within the oxygenation group, those receiving oxygenation for less than 10 minutes had higher umbilical artery pH values than those receiving oxygen for longer than 10 minutes.
REVIEWER'S CONCLUSIONS: There is not enough evidence to support the use of prophylactic oxygen therapy for women in labour, nor to evaluate its effectiveness for fetal distress.
产妇吸氧一直被用于试图通过增加来自母体的可用氧气来减轻胎儿窘迫。
本综述的目的是评估分娩期间产妇吸氧对胎儿窘迫的影响，并评估分娩第二产程期间预防性吸氧疗法对围产期结局的影响。
检索了Cochrane妊娠与分娩组试验注册库和Cochrane对照试验注册库。最后检索日期：1997年12月。
将分娩期间产妇吸氧治疗胎儿窘迫以及分娩第二产程期间预防性吸氧疗法与对照组（安慰剂或不吸氧治疗）进行比较的随机试验。
由综述作者评估纳入标准和试验质量。
未找到关于产妇吸氧治疗胎儿窘迫的试验。纳入了一项针对85名妇女的分娩期间预防性吸氧疗法的试验。与对照组相比，吸氧组脐血pH值低于7.2的情况更频繁出现（相对危险度4.83，95%置信区间1.11至21.04）。两组之间没有其他统计学上的显著差异。在吸氧组中，吸氧时间少于10分钟的产妇脐动脉pH值高于吸氧时间超过10分钟的产妇。
没有足够的证据支持对分娩妇女使用预防性吸氧疗法，也无法评估其对胎儿窘迫的有效性。
