[Lose-dose treatment with vitamin A in prevention of stress ulcer in swine].

Hemorrhagic shock in 8 piglets (mean AoBP 40 mm Hg for 3 h) was followed by severe stress-induced gastric mucosal lesions (Gr-I). When vitamin A was administered simultaneously (50,000 IE/kg = Gr. II, n = 6 and 5,000 IE/kg = Gr. III, n = 7) during the procedure, no stress lesions were observed. The study shows that the simultaneous application of vitamin A during hemorrhagic shock, in a reasonable clinical dosage, protects the gastric mucosa against stress-induced lesions.