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Comparison of vitamin C in plasma and leucocytes of smokers and non-smokers.吸烟者与非吸烟者血浆和白细胞中维生素C的比较。
Lancet. 1963 Mar 9;1(7280):556. doi: 10.1016/s0140-6736(63)91360-6.
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Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish Heart Health Study: cohort study.苏格兰心脏健康研究中27种不同因素对男性和女性冠心病及死亡预测的比较:队列研究
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Antioxidant vitamin intakes in Scottish smokers and nonsmokers. Dose effects and biochemical correlates.苏格兰吸烟者与非吸烟者抗氧化维生素的摄入量。剂量效应及生化关联。
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格拉斯哥第三次莫尼卡项目人群调查中的血浆维生素C水平与食物选择情况

Plasma vitamin C and food choice in the third Glasgow MONICA population survey.

作者信息

Wrieden W L, Hannah M K, Bolton-Smith C, Tavendale R, Morrison C, Tunstall-Pedoe H

机构信息

Centre for Applied Nutrition Research, Matthew Building, University of Dundee, DD1 4HT.

出版信息

J Epidemiol Community Health. 2000 May;54(5):355-60. doi: 10.1136/jech.54.5.355.

DOI:10.1136/jech.54.5.355
PMID:10814656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1731679/
Abstract

STUDY OBJECTIVE

To determine the contribution of different foods to the estimated intakes of vitamin C among those differing in plasma vitamin C levels, and thereby inform dietary strategies for correcting possible deficiency.

DESIGN

Cross sectional random population survey.

SETTING

North Glasgow, Scotland, 1992.

PARTICIPANTS

632 men and 635 women, aged 25 to 74 years, not taking vitamin supplements, who participated in the third MONICA study (population survey monitoring trends and determinants of cardiovascular disease).

MEASUREMENTS AND MAIN RESULTS

Dietary and sociodemographic information was collected using a food frequency and lifestyle questionnaire. Plasma vitamin C was measured in non-fasted venous blood samples and subjects categorised by cut points of 11.4 and 22.7 micromol/l as being of low, marginal or optimal vitamin C status. Food sources of dietary vitamin C were identified for subjects in these categories. Plasma vitamin C concentrations were compared among groups classified according to intake of key foods. More men (26%) than women (14%) were in the low category for vitamin C status; as were a higher percentage of smokers and of those in the older age groups. Intake of vitamin C from potatoes and chips (fried potatoes) was uniform across categories; while the determinants of optimal versus low status were the intakes of citrus fruit, non-citrus fruit and fruit juice. Optimal status was achieved by a combined frequency of fruit, vegetables and/or fruit juice of three times a day or more except in older male smokers where a frequency greater than this was required even to reach a marginal plasma vitamin C level.

CONCLUSION

Fruit, vegetables and/or fruit juice three or more times a day increases plasma vitamin C concentrations above the threshold for risk of deficiency.

摘要

研究目的

确定不同食物对血浆维生素C水平不同人群估计维生素C摄入量的贡献,从而为纠正可能的维生素C缺乏制定饮食策略提供依据。

设计

横断面随机人群调查。

地点

1992年,苏格兰格拉斯哥北部。

参与者

632名男性和635名女性,年龄在25至74岁之间,未服用维生素补充剂,参与了第三次莫尼卡研究(监测心血管疾病趋势和决定因素的人群调查)。

测量指标及主要结果

使用食物频率和生活方式问卷收集饮食和社会人口学信息。在非空腹静脉血样本中测量血浆维生素C,并根据11.4和22.7微摩尔/升的切点将受试者分为维生素C水平低、边缘或最佳状态。确定了这些类别中受试者饮食维生素C的食物来源。比较了根据关键食物摄入量分类的各组之间的血浆维生素C浓度。维生素C水平处于低类别中的男性(26%)多于女性(14%);吸烟者和老年人群体的比例也更高。土豆和薯片(炸土豆)中维生素C的摄入量在各类别中是一致的;而最佳状态与低状态的决定因素是柑橘类水果、非柑橘类水果和果汁的摄入量。除老年男性吸烟者外,每天食用水果、蔬菜和/或果汁三次或更多次可达到最佳状态,即使对于老年男性吸烟者,也需要高于此频率才能达到边缘血浆维生素C水平。

结论

每天食用三次或更多次水果、蔬菜和/或果汁可使血浆维生素C浓度高于缺乏风险阈值。