阿瑞他汀A和B，来自小单孢菌属TP-A0316的四环素类抗生素新成员。II. 结构测定。
Arisostatins A and B, new members of tetrocarcin class of antibiotics from Micromonospora sp. TP-A0316. II. Structure determination.
作者信息
Igarashi Y, Takagi K, Kan Y, Fujii K, Harada K, Furumai T, Oki T
机构信息
Biotechnology Research Center, Toyama Prefectural University, Kosugi, Japan.
出版信息
J Antibiot (Tokyo). 2000 Mar;53(3):233-40. doi: 10.7164/antibiotics.53.233.
PMID:10819293
Abstract
Structures of arisostatins A and B were determined by spectroscopic analyses. Arisostatins were found to be new analogs of tetrocarcin A and possess an iso-butanoyldigitoxose unit instead of the acetyldigitoxose one. NMR analyses of arisostatins and tetrocarcin A led to the revision of the anomeric configurations in the tetrasaccharide moiety of tetrocarcin A.
摘要
通过光谱分析确定了阿里司他汀A和B的结构。发现阿里司他汀是四癌菌素A的新类似物，并且具有异丁酰基洋地黄毒糖单元而非乙酰基洋地黄毒糖单元。对阿里司他汀和四癌菌素A的核磁共振分析导致了四癌菌素A四糖部分端基构型的修正。
Zotero 插件