Genard P, Palem-Vliers M, van Cauwenberge H, Eechaute W
Endocrinol Exp. 1976 Mar;10(1):53-8.
The detection of two unknown urinary steroids called x and y in various patients was previously reported. Compound x was tentatively characterized as a derivative of dihydro-18-hydroxy-DOC with two additional polar groups. In this communication clinical observations of a set of 25 hypertensive patients are presented. Compound x alone was found in 4 cases, compound y alone 4 cases and both compound x and y in 5 cases. In several other cases, hypokalemia and/or a decreased urinary Na+/K+ ratio were found.
先前已有报道在各类患者中检测到两种未知的尿甾体化合物，分别称为x和y。化合物x初步被鉴定为二氢-18-羟基-脱氧皮质酮的衍生物，带有另外两个极性基团。在本报告中，展示了一组25例高血压患者的临床观察结果。仅发现化合物x的有4例，仅发现化合物y的有4例，同时发现化合物x和y的有5例。在其他几例患者中，发现了低钾血症和/或尿钠/钾比值降低。
