Baaske D M, Carter J E, Amann A H
J Pharm Sci. 1979 Apr;68(4):481-3. doi: 10.1002/jps.2600680423.
A rapid high-pressure liquid chromatographic method for determining the nitroglycerin concentration in liquid dosage forms and intravenous admixture solutions is presented. A coefficient of variation of less than 1.8% was achieved over the concentration range most commonly encountered (50-500 microgram/ml). A variable wavelength detector (lambda = 218 nm) and a micro-alkyl phenyl column were employed. The mobile phase was acetonitrile-tetrahydrofuran-water (26:10:64). Total analysis time was 12 min.
本文介绍了一种用于测定液体制剂和静脉混合溶液中硝酸甘油浓度的快速高压液相色谱法。在最常遇到的浓度范围（50 - 500微克/毫升）内，变异系数小于1.8%。采用可变波长检测器（λ = 218纳米）和微烷基苯基柱。流动相为乙腈 - 四氢呋喃 - 水（26:10:64）。总分析时间为12分钟。
