Chorlton P, Kane N
Grey Walter Department of Neurophysiology, Frenchay Hospital, Bristol, U.K.
Clin Electroencephalogr. 2000 Apr;31(2):83-7. doi: 10.1177/155005940003100206.
Migraine affects 10% of the population, yet there is no proven diagnostic test. To date the most promising neurophysiological diagnostic technique has been the analysis of cerebral responses to photic stimulation or flicker (the "H" response). This test has proved to be sensitive in patients with "classic" migraine, but has not been re-evaluated since the introduction of the 1988 International Headache Society (IHS) classification system. In 33 migraineurs, we found that the "H" response was sensitive (86.4%) and specific (97.5%) in those with migraine defined according to IHS Committee as type 1.2.1 (typical aura) and type 1.1 (without aura), but not in basilar migraine (1.2.4).
偏头痛影响着10%的人口，但目前尚无经证实的诊断测试。迄今为止，最有前景的神经生理学诊断技术是分析大脑对光刺激或闪烁的反应（“H”反应）。这项测试已被证明对“典型”偏头痛患者敏感，但自1988年国际头痛协会（IHS）分类系统引入以来，尚未重新评估。在33名偏头痛患者中，我们发现，根据IHS委员会定义，“H”反应对1.2.1型（典型先兆）和1.1型（无先兆）偏头痛患者敏感（86.4%）且特异（97.5%），但对基底型偏头痛（1.2.4）患者不敏感。
