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本文引用的文献

1
Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms.基质金属蛋白酶-9（明胶酶B）的靶向基因破坏抑制实验性腹主动脉瘤的发展。
J Clin Invest. 2000 Jun;105(11):1641-9. doi: 10.1172/JCI8931.
2
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.抑制纤溶酶原激活剂或基质金属蛋白酶可预防心脏破裂，但会损害治疗性血管生成并导致心力衰竭。
Nat Med. 1999 Oct;5(10):1135-42. doi: 10.1038/13459.
3
MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial.腹主动脉瘤中的基质金属蛋白酶抑制：一项前瞻性随机临床试验的理论依据
Ann N Y Acad Sci. 1999 Jun 30;878:159-78. doi: 10.1111/j.1749-6632.1999.tb07682.x.
4
Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice.基质金属蛋白酶抑制可减轻小鼠实验性心肌梗死后早期左心室扩大。
Circulation. 1999 Jun 15;99(23):3063-70. doi: 10.1161/01.cir.99.23.3063.
5
Experimental techniques and models in the study of the development and treatment of abdominal aortic aneurysm.腹主动脉瘤发展与治疗研究中的实验技术与模型
Br J Surg. 1999 Mar;86(3):305-12. doi: 10.1046/j.1365-2168.1999.01092.x.
6
Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms.巨噬细胞弹性蛋白酶（基质金属蛋白酶-12）在腹主动脉瘤中的表达及定位
J Clin Invest. 1998 Dec 1;102(11):1900-10. doi: 10.1172/JCI2182.
7
Reduced transplant arteriosclerosis in plasminogen-deficient mice.纤溶酶原缺陷小鼠的移植动脉硬化减轻。
J Clin Invest. 1998 Nov 15;102(10):1788-97. doi: 10.1172/JCI3316.
8
Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model.在大鼠模型中，组织金属蛋白酶抑制剂-1（TIMP-1）的局部过表达可防止主动脉瘤退变和破裂。
J Clin Invest. 1998 Oct 1;102(7):1413-20. doi: 10.1172/JCI2909.
9
Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1.
Circulation. 1998 Jul 21;98(3):249-55. doi: 10.1161/01.cir.98.3.249.
10
Postinfarction ventricular septal rupture: the Wessex experience.心肌梗死后室间隔破裂：韦塞克斯地区的经验
Semin Thorac Cardiovasc Surg. 1998 Apr;10(2):111-6. doi: 10.1016/s1043-0679(98)70004-8.

Proteinases in cardiovascular aneurysms and rupture: targets for therapy?

作者信息

Carmeliet P

机构信息

The Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, KU Leuven, Leuven, Belgium.

出版信息

J Clin Invest. 2000 Jun;105(11):1519-20. doi: 10.1172/JCI10242.

DOI:10.1172/JCI10242
PMID:10841508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC300866/
Abstract
摘要