Hosking D J, Chamberlain M J, Shortland-Webb W R
Br J Radiol. 1975 Jun;48(570):451-6. doi: 10.1259/0007-1285-48-570-451.
A case of hypophosphataemic osteomalacia occurring in association with a carcinoma of prostate is described. Although only palliative treatment to the primary tumour was possible, worthwhile remission of bone symptoms, due to osteomalacia, was achieved with pharmacological doses of vitamin D. The presence of extensive skeletal metastases modified the radiological features of osteomalacia. Major alterations in the distribution of calcium within the skeleton were observed during a period when total body calcium remained unaltered. This observation may be of relevance to other cases in which osteosclerotic metastases develop.
本文描述了一例与前列腺癌相关的低磷性骨软化症病例。尽管对原发肿瘤仅进行了姑息性治疗，但通过给予药理剂量的维生素D，骨软化症所致的骨症状得到了显著缓解。广泛的骨转移改变了骨软化症的放射学特征。在全身钙含量保持不变的时期内，观察到骨骼内钙分布发生了重大变化。这一观察结果可能与发生骨硬化性转移的其他病例相关。
