Takeshi K, Homma J Y
Jpn J Exp Med. 1978 Dec;48(6):497-501.
Passive hemagglutination (PHA) tests using fixed sheep erythrocytes coated with exotoxin of Pseudomonas aeruginosa were devised for estimating antibodies of the exotoxin. No serological cross-reactivity among exotoxin OEP, protease and elastase of P. aeruginosa was foud by the PHA tests. The exotoxin PHA reaction was more sensitive than the neutralizing reaction of skin necrotizing activity of exotoxin by guinea pigs. Thirteen out of 40 sera of patients with P. aeruginosa infections showed PHA titers from 40 to 1,280, while those of 20 healthy human sera were under 40.
采用包被有铜绿假单胞菌外毒素的固定绵羊红细胞进行被动血凝试验（PHA），以检测外毒素抗体。通过PHA试验未发现铜绿假单胞菌外毒素OEP、蛋白酶和弹性蛋白酶之间存在血清学交叉反应。外毒素PHA反应比豚鼠对皮肤坏死活性外毒素的中和反应更敏感。40例铜绿假单胞菌感染患者的血清中，有13例PHA滴度为40至1280，而20例健康人血清的PHA滴度低于40。
