Ahuja Y R, Vijayashree B, Saran R, Jayashri E L, Manoranjani J K, Bhargava S C
Genetics Unit, Bhagwan Mahavir Medical Research Centre, Hyderabad.
Indian J Biochem Biophys. 1999 Oct;36(5):318-22.
The sources for the effects of electromagnetic fields (EMFs) have been traced to time-varying as well as steady electric and magnetic fields, both at low and high to ultra high frequencies. Of these, the effects of low-frequency (50/60 HZ) magnetic fields, directly related to time-varying currents, are of particular interest as exposure to some fields may be commonly experienced. In the present study, investigations have been carried out at low-level (mT) and low-frequency (50 Hz) electromagnetic fields in healthy human volunteers. Their peripheral blood samples were exposed to 5 doses of electromagnetic fields (2,3,5,7 and 10mT at 50 Hz) and analysed by comet assay. The results were compared to those obtained from unexposed samples from the same subjects. 50 cells per treatment per individual were scored for comet-tail length which is an estimate of DNA damage. Data from observations among males were pooled for each flux density for analysis. At each flux density, with one exception, there was a significant increase in the DNA damage from the control value. When compared with a similar study on females carried out by us earlier, the DNA damage level was significantly higher in the females as compared to the males for each flux density.
电磁场（EMFs）效应的来源已追溯到随时间变化以及稳定的电场和磁场，涵盖低频到高频乃至超高频范围。其中，与随时间变化的电流直接相关的低频（50/60赫兹）磁场效应尤为引人关注，因为人们可能普遍会接触到某些此类磁场。在本研究中，对健康人类志愿者进行了低强度（毫特斯拉）和低频（50赫兹）电磁场的研究。他们的外周血样本暴露于5种剂量的电磁场（50赫兹时为2、3、5、7和10毫特斯拉），并通过彗星试验进行分析。将结果与同一受试者未暴露样本的结果进行比较。对每个个体每次处理的50个细胞进行彗星尾长评分，彗星尾长是DNA损伤的一个指标。将男性观察的数据按每个通量密度汇总进行分析。在每个通量密度下，除了一个例外，DNA损伤均比对照值有显著增加。与我们之前对女性进行的类似研究相比，在每个通量密度下，女性的DNA损伤水平均显著高于男性。
