Pacchetti C, Mancini F, Aglieri R, Fundarò C, Martignoni E, Nappi G
Parkinson's Disease and Movement Disorders Centre, Istituto di Ricerca e Cura a Carattere Scientifico C. Mondino, University of Pavia, Italy.
Psychosom Med. 2000 May-Jun;62(3):386-93. doi: 10.1097/00006842-200005000-00012.
Modern management of Parkinson's disease (PD) aims to obtain symptom control, to reduce clinical disability, and to improve quality of life. Music acts as a specific stimulus to obtain motor and emotional responses by combining movement and stimulation of different sensory pathways. We explored the efficacy of active music therapy (MT) on motor and emotional functions in patients with PD.
This prospective, randomized, controlled, single-blinded study lasted 3 months. It consisted of weekly sessions of MT and physical therapy (PT). Thirty-two patients with PD, all stable responders to levodopa and in Hoehn and Yahr stage 2 or 3, were randomly assigned to two groups of 16 patients each. We assessed severity of PD with the Unified Parkinson's Disease Rating Scale, emotional functions with the Happiness Measure, and quality of life using the Parkinson's Disease Quality of Life Questionnaire. MT sessions consisted of choral singing, voice exercise, rhythmic and free body movements, and active music involving collective invention. PT sessions included a series of passive stretching exercises, specific motor tasks, and strategies to improve balance and gait.
MT had a significant overall effect on bradykinesia as measured by the Unified Parkinson's Disease Rating Scale (p < .034). Post-MT session findings were consistent with motor improvement, especially in bradykinesia items (p < .0001). Over time, changes on the Happiness Measure confirmed a beneficial effect of MT on emotional functions (p < .0001). Improvements in activities of daily living and in quality of life were also documented in the MT group (p < .0001). PT improved rigidity (p < .0001).
MT is effective on motor, affective, and behavioral functions. We propose active MT as a new method for inclusion in PD rehabilitation programs.
帕金森病（PD）的现代管理旨在实现症状控制、减少临床残疾并提高生活质量。音乐通过结合运动和对不同感觉通路的刺激，作为一种特定的刺激来引发运动和情感反应。我们探讨了主动音乐疗法（MT）对PD患者运动和情感功能的疗效。
这项前瞻性、随机、对照、单盲研究持续了3个月。它包括每周一次的MT和物理治疗（PT）。32例PD患者，均为对左旋多巴反应稳定且处于Hoehn和Yahr 2期或3期，被随机分为两组，每组16例。我们使用统一帕金森病评定量表评估PD的严重程度，使用幸福度量表评估情感功能，并使用帕金森病生活质量问卷评估生活质量。MT课程包括合唱、发声练习、有节奏和自由的身体运动以及涉及集体创作的主动音乐。PT课程包括一系列被动伸展运动、特定的运动任务以及改善平衡和步态的策略。
通过统一帕金森病评定量表测量，MT对运动迟缓有显著的总体影响（p < .034）。MT课程后的结果与运动改善一致，尤其是在运动迟缓项目上（p < .0001）。随着时间的推移，幸福度量表上的变化证实了MT对情感功能的有益影响（p < .0001）。MT组在日常生活活动和生活质量方面也有改善（p < .0001）。PT改善了僵硬程度（p < .0001）。
MT对运动、情感和行为功能有效。我们建议将主动MT作为一种新方法纳入PD康复计划。
