Mazumder D N, Mitra A C, Mukherjee M K
Bull World Health Organ. 1975;52(3):301-6.
The paper presents clinical observations on 1 233 persons with smallpox who were admitted to the Infectious Diseases Hospital, Calcutta, in 1973. The disease was of the modified type in 53 patients (4.3%), the ordinary type in 717 (58.2%), the flat type in 249 (20.2%), and the haemorrhagic type in 214 (17.3%). The fatality of these types of smallpox was found to be 5.7%, 26.8%, 88.4%, and 98.1%, respectively, and the overall case fatality was 50.7%. The haemorrhagic type was found mainly among older patients and affected males more often than females. The vaccination status of 1 218 patients was known. Of these, 901 (73.9%) were unvaccinated and had a fatality rate of 53.4%, whereas the 317 (26.1%) vaccinated patients had a fatality rate of 36.5%. Among the 201 haemorrhagic cases, 145 patients were unvaccinated (16.09% of the total number unvaccinated) and 56 (17.67%) had been vaccinated. Of 34 patients vaccinated during the incubation period, 19 (41.1%) died, whereas of 18 patients who had been vaccinated after the onset of fever, but before the appearance of rash, 9 (50%) died.
该论文介绍了1973年收治于加尔各答传染病医院的1233例天花患者的临床观察情况。其中，53例（4.3%）为改良型天花，717例（58.2%）为普通型天花，249例（20.2%）为扁平型天花，214例（17.3%）为出血型天花。这些类型天花的病死率分别为5.7%、26.8%、88.4%和98.1%，总体病死率为50.7%。出血型天花主要见于老年患者，男性受累多于女性。已知1218例患者的疫苗接种情况。其中，901例（73.9%）未接种疫苗，病死率为53.4%；而317例（26.1%）接种疫苗的患者病死率为36.5%。在201例出血型病例中，145例患者未接种疫苗（占未接种总数的16.09%），56例（17.67%）接种过疫苗。在潜伏期接种疫苗的34例患者中，19例（41.1%）死亡；而在发热开始后、出疹前接种疫苗的18例患者中，9例（50%）死亡。
