Celikoğlu S I, Göksel F M, Bilgin T
Ann N Y Acad Sci. 1976;278:125-8. doi: 10.1111/j.1749-6632.1976.tb47023.x.
IgG, IgA, and IgM immunoglobulins and alpha-1-antitrypsin globulin in sera from 30 patients with lepromatous leprosy were determined and compared with 30 age- and sex-matched healthy controls. Mean levels of IgG, IgM, IgA, and alpha-1-antitrypsin were significantly elevated in the sera of lepromatous leprosy patients in comparison with levels found in normal subjects. Statistical analysis of the relationships between levels of alpha-1-antitrypsin and immunoglobulins in the sera of lepromatous leprosy patients and controls revealed no correlation. It is therefore concluded that factors responsible for concentrations of immunoglobulins and alpha-1-antitrypsin are independent of each other in patients with lepromatous leprosy.
测定了30例瘤型麻风患者血清中的IgG、IgA和IgM免疫球蛋白以及α-1抗胰蛋白酶球蛋白，并与30例年龄和性别匹配的健康对照进行比较。与正常受试者相比，瘤型麻风患者血清中IgG、IgM、IgA和α-1抗胰蛋白酶的平均水平显著升高。对瘤型麻风患者和对照血清中α-1抗胰蛋白酶水平与免疫球蛋白水平之间的关系进行统计分析，结果显示无相关性。因此得出结论，在瘤型麻风患者中，负责免疫球蛋白和α-1抗胰蛋白酶浓度的因素相互独立。
