Wong A Y, Wong K, Tang L C
Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Kowloon, Hong Kong, China.
Fertil Steril. 2000 Jun;73(6):1234-7. doi: 10.1016/s0015-0282(00)00498-2.
To assess the efficacy of lignocaine gel in reducing the overall pain and pain of individual steps during outpatient hysteroscopy in comparison with placebo (no anesthesia).
A prospective, randomized, double-blind, placebo-controlled trial.
Outpatient hysteroscopy clinic in a regional hospital in Hong Kong.
PATIENT(S): A total of 500 Chinese patients undergoing outpatient hysteroscopy.
INTERVENTION(S): Application of lignocaine gel to the cervix during outpatient hysteroscopy.
MAIN OUTCOME MEASURE(S): Mean pain score using present pain intensity, overall pain score measured by total area under the curve, and the pain score of individual steps in the procedure in patients receiving lignocaine gel were compared with those of patients having no anesthesia. The failure rate and poor-view rate in both groups were also compared.
RESULT(S): There were no statistically significant differences in mean pain score, overall pain score, and pain score of individual steps between the lignocaine group and controls. The failure rate and poor-view rate also showed no statistically significant differences.
CONCLUSION(S): Outpatient hysteroscopy without anesthesia is acceptable to most Chinese women, and the local application of lignocaine gel is not effective in reducing pain.
与安慰剂（无麻醉）相比，评估利多卡因凝胶在减轻门诊宫腔镜检查期间总体疼痛及各个步骤疼痛方面的疗效。
一项前瞻性、随机、双盲、安慰剂对照试验。
香港一家地区医院的门诊宫腔镜检查诊所。
总共500名接受门诊宫腔镜检查的中国患者。
在门诊宫腔镜检查期间将利多卡因凝胶应用于宫颈。
使用当前疼痛强度的平均疼痛评分、通过曲线下总面积测量的总体疼痛评分，以及接受利多卡因凝胶的患者在手术各个步骤的疼痛评分，与未接受麻醉的患者进行比较。还比较了两组的失败率和视野不佳率。
利多卡因组与对照组在平均疼痛评分、总体疼痛评分及各个步骤的疼痛评分方面无统计学显著差异。失败率和视野不佳率也无统计学显著差异。
大多数中国女性可接受无麻醉的门诊宫腔镜检查，局部应用利多卡因凝胶在减轻疼痛方面无效。
