Rao S K, Fogla R, Seethalakshmi G, Padmanabhan P
Medical Research Foundation, Chennai, India.
Indian J Ophthalmol. 1999 Sep;47(3):167-72.
To report indications, technique, and results of excimer phototherapeutic keratectomy (PTK), and describe possible reasons for the small numbers of such procedures performed in a referral institute in India.
Retrospective review of case records of 10 patients (11 eyes) who underwent excimer PTK at our institute between February 1994 and September 1997.
Corneal scars were the most common indication for treatment. Best-corrected visual acuity (BCVA) improved in 6 eyes (mean: 2 lines of Snellen acuity). All eyes had BCVA > or = 6/12 after treatment. None of the patients experienced loss of BCVA after treatment. Unaided visual acuity improved in 3 eyes and decreased in 2 eyes. Change in spherical equivalent refraction > or = 1 diopter occurred in 77.8% of eyes after treatment. Treating central corneal scars resulted in a significant hyperopic shift in refraction.
Excimer PTK is a safe and effective procedure for the treatment of superficial corneal opacities. Post-treatment ametropia may require further correction with optical aids. Inappropriate referrals, deep corneal scars, and cost of the procedure could have contributed to the small numbers of PTK performed at our institute. Improved understanding of procedural strengths and limitations could lead to increased use of this procedure, with satisfying results in selected patients.
报告准分子光治疗性角膜切削术（PTK）的适应证、技术及结果，并描述在印度一家转诊机构中此类手术数量较少的可能原因。
回顾性分析1994年2月至1997年9月间在我院接受准分子PTK的10例患者（11只眼）的病例记录。
角膜瘢痕是最常见的治疗适应证。6只眼的最佳矫正视力（BCVA）得到改善（平均：Snellen视力提高2行）。所有眼治疗后BCVA≥6/12。治疗后无一例患者BCVA下降。裸眼视力3只眼提高，2只眼下降。治疗后77.8%的眼等效球镜度变化≥1屈光度。治疗中央角膜瘢痕导致明显的远视性屈光偏移。
准分子PTK是治疗浅层角膜混浊的一种安全有效的方法。治疗后屈光不正可能需要进一步借助光学辅助器具进行矫正。转诊不当、深层角膜瘢痕以及手术费用可能是导致我院PTK手术数量较少的原因。更好地了解该手术的优势和局限性可能会增加该手术的应用，从而使部分患者获得满意的结果。
