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小鼠抗体形成细胞系的个体发生。I. 成熟B细胞出现的动力学

Ontogeny of the antibody-forming cell line in mice. I. Kinetics of appearance of mature B cells.

作者信息

Rosenberg Y J, Cunningham A J

出版信息

Eur J Immunol. 1976 Jul;5(7):444-7. doi: 10.1002/eji.1830050703.

DOI:10.1002/eji.1830050703
PMID:1086243
Abstract

The development of functionally mature B cells in the liver and spleen of fetal and neonatal CBA mice has been followed. A mature B cell is defined as one giving rise to antibody-producing progeny within 2 days in culture. Very few such B cells are found during fetal life. After birth there is a rapid rise in the numbers reaching 1/3 of adult levels in the 7-day-old spleen.

摘要

对胎儿和新生CBA小鼠肝脏和脾脏中功能成熟B细胞的发育过程进行了追踪。成熟B细胞定义为在培养2天内能够产生抗体的子代细胞。在胎儿期，很少发现这类B细胞。出生后，其数量迅速增加，在7日龄小鼠的脾脏中达到成年水平的1/3。

相似文献

1
Ontogeny of the antibody-forming cell line in mice. I. Kinetics of appearance of mature B cells.小鼠抗体形成细胞系的个体发生。I. 成熟B细胞出现的动力学
Eur J Immunol. 1976 Jul;5(7):444-7. doi: 10.1002/eji.1830050703.
2
Ontogeny of the antibody-forming cell line in mice. II. Maturation of B cells during fetal development.小鼠抗体形成细胞系的个体发生。II. 胎儿发育过程中B细胞的成熟。
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Ontogeny of the antibody-forming cell line in mice. IV. Appearance of cells bearing Fc receptors, complement receptors, and surface immunoglobulin.小鼠抗体形成细胞系的个体发生。IV. 带有Fc受体、补体受体和表面免疫球蛋白的细胞的出现。
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Changes in B lineage cell population in liver and spleen of normal neonatal mice.正常新生小鼠肝脏和脾脏中B淋巴细胞群体的变化。
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Ontogeny of mouse T-lymphocyte function.小鼠T淋巴细胞功能的个体发生
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In vivo generation and function of B cells in the presence of a monoclonal anti-IgM antibody: implications for B cell tolerance.在单克隆抗IgM抗体存在情况下B细胞的体内生成及功能：对B细胞耐受性的影响
Eur J Immunol. 1987 Jul;17(7):981-90. doi: 10.1002/eji.1830170714.

引用本文的文献

1
Immune system as a target organ for toxicity.作为毒性作用靶器官的免疫系统。
Environ Health Perspect. 1982 Feb;43:3-7. doi: 10.1289/ehp.82433.
2
Background (spontaneous) immunoglobulin production in the murine small intestine as a function of age.小鼠小肠中（自发）免疫球蛋白产生随年龄的变化情况。
Immunology. 1988 Oct;65(2):243-8.
3
Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance.新生和成年小鼠脾细胞对体外诱导B细胞耐受性的差异敏感性。
J Exp Med. 1976 Jul 1;144(1):293-7. doi: 10.1084/jem.144.1.293.
4
Age-dependent variations of antibody avidity.抗体亲和力的年龄依赖性变化。
Immunology. 1978 Oct;35(4):601-11.
5
Functional maturation of neonatal spleen cells.新生脾脏细胞的功能成熟
Immunology. 1979 Mar;36(3):527-32.
6
Ontogeny of cell-mediated immunity. I. Early development of alloantigen-specific cytotoxic T-cell precursors in postnatal mice.细胞介导免疫的个体发生。I. 新生小鼠中同种异体抗原特异性细胞毒性T细胞前体的早期发育。
J Exp Med. 1977 Sep 1;146(3):887-92. doi: 10.1084/jem.146.3.887.
7
Ontogeny of B-lymphocyte function. V. Thymus cell involvement in the functional maturation of B-lymphocytes from fetal mice transferred into adult irradiated hosts.B淋巴细胞功能的个体发生。V. 胸腺细胞参与转入成年受辐照宿主的胎鼠B淋巴细胞的功能成熟过程。
J Exp Med. 1978 Jan 1;147(1):196-206. doi: 10.1084/jem.147.1.196.