Hackenberg K, Cohnen G, Reinwein D
Klin Wochenschr. 1976 Oct 15;54(20):987-93. doi: 10.1007/BF01468950.
Thymus-derived peripheral blood lymphocytes were studied in untreated (n = 18), methimazole-treated (n = 28) thyrotoxicosis, after radioiodine (n = 14), in Hashimoto thyroiditis (n = 7) and in euthyroid goiter (n = 7). The results were compared with normal persons (n = 40) without thyroid disease. There was no significant difference in the total and relative counts of T-cells either between the different groups nor compared with the controls. These findings confirm that T-cells in peripheral blood cannot give any information about activity or prognosis of the various thyroid diseases. Thus T-cells give no further suggestion concerning the possible pathogenetic role of cell-mediated-immunity.
对未经治疗的甲状腺毒症患者（n = 18）、甲巯咪唑治疗的甲状腺毒症患者（n = 28）、放射性碘治疗后的患者（n = 14）、桥本甲状腺炎患者（n = 7）和甲状腺功能正常的甲状腺肿患者（n = 7）的胸腺来源外周血淋巴细胞进行了研究。将结果与无甲状腺疾病的正常人群（n = 40）进行比较。不同组之间以及与对照组相比，T细胞的总数和相对计数均无显著差异。这些发现证实，外周血中的T细胞无法提供有关各种甲状腺疾病活动或预后的任何信息。因此，T细胞对于细胞介导免疫可能的致病作用没有进一步的提示。
