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白塞病中淋巴细胞功能的各个方面。

Aspects of lymphocyte function in Behçet's disease.

作者信息

Haim S, Mekori T, Sobel J D, Robinson E

出版信息

Dermatologica. 1976;153(1):34-7. doi: 10.1159/000251104.

DOI:10.1159/000251104
PMID:1086808
Abstract

Aspects of lymphocyte function were investigated, in vitro, in nine patients with active Behçet's disease. The rosette formation technique revealed a slight decrease in number of T lymphocytes and more so of B lymphocytes. In spite of their low number, the transformation of the T lymphocytes in response to mitogens did not show a significant difference from that of normal controls. This may indicate a hyperreactivity, and in two instances a spontaneous blastogenesis prior to addition of mitogens, was also noted. The immunoglobulins and complement levels in serum were within normal limits.

摘要

对9例活动期白塞病患者的淋巴细胞功能进行了体外研究。玫瑰花结形成技术显示T淋巴细胞数量略有减少,B淋巴细胞数量减少更明显。尽管数量较少,但T淋巴细胞对有丝分裂原的反应转化与正常对照组相比没有显著差异。这可能表明存在高反应性,并且在两例中还注意到在添加有丝分裂原之前有自发的细胞分裂。血清中的免疫球蛋白和补体水平在正常范围内。

相似文献

1
Aspects of lymphocyte function in Behçet's disease.白塞病中淋巴细胞功能的各个方面。
Dermatologica. 1976;153(1):34-7. doi: 10.1159/000251104.
2
[Immunological study of Behcet's disease].
Bull Soc Pathol Exot Filiales. 1978 Mar-Apr;71(2):221-6.
3
Abnormal B cell function in patients with Behçet's disease.白塞病患者的B细胞功能异常。
Arthritis Rheum. 1986 Feb;29(2):212-9. doi: 10.1002/art.1780290209.
4
Lymphocyte studies in Behçet's syndrome.
Dermatologica. 1982 Mar;164(3):175-80. doi: 10.1159/000250087.
5
Cell-mediated immune functions and immunoregulatory cells in Behçet's syndrome.白塞病中的细胞介导免疫功能和免疫调节细胞。
Clin Exp Immunol. 1982 Apr;48(1):121-8.
6
Behçet's disease: clinical and immunological response to immunosuppressive therapy. A case report.白塞病:免疫抑制治疗的临床及免疫学反应。病例报告。
Isr J Med Sci. 1985 Jan;21(1):57-61.
7
Functional aberration of T cell subsets in patients with Behçet's disease.白塞病患者T细胞亚群的功能异常。
Arthritis Rheum. 1982 Nov;25(11):1343-51. doi: 10.1002/art.1780251110.
8
Analysis of interleukin-2 activity in patients with Behçet's disease. Ability of T cells to produce and respond to interleukin-2.白塞病患者白细胞介素-2活性分析。T细胞产生和对白介素-2作出反应的能力。
Arthritis Rheum. 1986 Mar;29(3):371-8. doi: 10.1002/art.1780290310.
9
Evaluation of T cell subsets in Behçet's syndrome using anti-T cell monoclonal antibodies.使用抗T细胞单克隆抗体评估白塞病中的T细胞亚群。
Clin Exp Immunol. 1985 Apr;60(1):55-60.
10
Abnormalities of T-cell subsets in Behçet's syndrome.白塞病中T细胞亚群的异常。
Arch Dermatol. 1983 Apr;119(4):307-10.

引用本文的文献

1
Lymphocyte studies in a patient with neurological complications of Behçet's syndrome.白塞综合征神经并发症患者的淋巴细胞研究
Clin Rheumatol. 1982 Jun;1(2):131-5. doi: 10.1007/BF02275604.
2
Behçet syndrome: report of two early-onset cases treated with transfer factor.白塞综合征:两例早发型病例应用转移因子治疗的报告。
Ital J Neurol Sci. 1984 Mar;5(1):93-6. doi: 10.1007/BF02043978.
3
Epidermal Langerhans' cells in Behçet's disease.白塞病中的表皮朗格汉斯细胞。
J Clin Pathol. 1984 Jun;37(6):616-9. doi: 10.1136/jcp.37.6.616.