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饮酒与动脉粥样硬化。

Alcohol consumption and atherosclerosis.

作者信息

Lifsic A M

出版信息

Bull World Health Organ. 1976;53(5-6):623-30.

PMID:1087205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2366547/
Abstract

A study was made of the material obtained in 737 autopsies carried out on men aged 30-69 years (including 88 visitors) who had died in Yalta from various diseases, accidents, and violence. Information on the consumption of alcohol was obtained by questioning the subjects' near relations, neighbours, and associates, as well as from medical records. The most reliable part of this information-the average number of days per month on which the subject consumed alcohol-was taken as the basic criterion for grouping the observations. People taking alcohol on 16 or more days per month had more extensive atherosclerotic raised lesions in the aorta than those drinking on not more than 3 days per month. This difference was most significant in the case of calcified lesions. Fatty streak in the aorta was more extensive in the medium group (drinking on 4-15 days per month) than in either of the extreme groups. As regards the coronary arteries, a significant difference positively associated with alcohol consumption was established only in the case of calcification. The few differences concerning myocardial and cerebral infarction had a negative association with alcohol consumption.

摘要

对737例年龄在30至69岁男性(包括88名访客)的尸体解剖材料进行了研究,这些男性在雅尔塔死于各种疾病、事故和暴力。通过询问受试者的近亲、邻居和同事以及查阅医疗记录获取饮酒信息。该信息中最可靠的部分——受试者每月饮酒的平均天数——被用作对观察结果进行分组的基本标准。每月饮酒16天及以上的人主动脉粥样硬化隆起病变比每月饮酒不超过3天的人更广泛。这种差异在钙化病变方面最为显著。主动脉中的脂肪条纹在中等饮酒组(每月饮酒4至15天)中比在两个极端饮酒组中都更广泛。关于冠状动脉,仅在钙化方面发现与饮酒呈正相关的显著差异。关于心肌梗死和脑梗死的少数差异与饮酒呈负相关。

相似文献

1
Alcohol consumption and atherosclerosis.饮酒与动脉粥样硬化。
Bull World Health Organ. 1976;53(5-6):623-30.
2
Atherosclerosis in smokers.吸烟者的动脉粥样硬化
Bull World Health Organ. 1976;53(5-6):631-8.
3
Atherosclerosis and myocardial disease in relation to physical activity of occupation.与职业体力活动相关的动脉粥样硬化和心肌病
Bull World Health Organ. 1976;53(5-6):615-22.
4
Atherosclerosis and diabetes mellitus.动脉粥样硬化与糖尿病
Bull World Health Organ. 1976;53(5-6):547-53.
5
Coronary and aortic atherosclerosis in relation to occupational physical activity in male violent deaths.
Ann Clin Res. 1975 Dec;7(6):394-401.
6
Prevalence of atherosclerosis of the aorta in Ethiopians: a postmortem study.
East Afr Med J. 1992 Apr;69(4):214-8.
7
Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men.饮酒模式及所饮用酒精类型在男性冠心病中的作用。
N Engl J Med. 2003 Jan 9;348(2):109-18. doi: 10.1056/NEJMoa022095.
8
Atherosclerosis of the aorta in five towns.五个城镇的主动脉粥样硬化情况。
Bull World Health Organ. 1976;53(5-6):501-8.
9
Atherosclerosis of the coronary arteries in five towns.五个城镇的冠状动脉粥样硬化情况。
Bull World Health Organ. 1976;53(5-6):509-18.
10
Atherosclerosis and hypertension.动脉粥样硬化与高血压。
Bull World Health Organ. 1976;53(5-6):539-46.

本文引用的文献

1
Serum cholesterol in man: diet fat and intrinsic responsiveness.人类血清胆固醇:膳食脂肪与内在反应性。
Circulation. 1959 Feb;19(2):201-14. doi: 10.1161/01.cir.19.2.201.
2
Haemodynamic effects of ethyl alcohol in patients with coronary heart disease.乙醇对冠心病患者的血流动力学影响。
Br Heart J. 1968 Sep;30(5):638-44. doi: 10.1136/hrt.30.5.638.
3
The concept of alcoholic myocardiopathy.酒精性心肌病的概念。
Med Clin North Am. 1968 Sep;52(5):1183-91.