表面免疫球蛋白在运动性B淋巴细胞中的自发再分布。
Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte.
作者信息
Schreiner G F, Braun J, Unanue E R
出版信息
J Exp Med. 1976 Dec 1;144(6):1683-8. doi: 10.1084/jem.144.6.1683.
Abstract
This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin A-dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.
摘要
本文报道，正在进行平移运动的B细胞会自发地将其表面免疫球蛋白聚集到质膜的一部分。表面免疫球蛋白的自发重新分布被发现具有以下特点：（a）具有选择性，依赖于伴刀豆球蛋白A、平移运动和能量代谢。在用脂多糖或胰蛋白酶培养后，或在短暂暴露于胆碱能药物后，发现有大量进行运动的B细胞。
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