Rebec G V, Segal D S
Psychopharmacology (Berl). 1979 Mar 29;62(1):101-2. doi: 10.1007/BF00426043.
Previous studies have demonstrated that long-term administration of d-amphetamine produces a progressive augmentation of behavior. In the present experiment, rats receiving repeated systemic injections responded to an intraventricular infusion of d-amphetamine with an augmented increase in locomotor activity. These results indicate that central mechanisms, rather than peripheral dispositional factors, subserve the enhanced behavioral response to repeated amphetamine administration.
先前的研究表明，长期给予右旋苯丙胺会使行为逐渐增强。在本实验中，接受反复全身注射的大鼠对脑室内注入右旋苯丙胺的反应是运动活动增强。这些结果表明，是中枢机制而非外周处置因素促进了对反复给予苯丙胺的行为反应增强。
