Bukharin O V, Gritsenko V A
Research Institute of Cellular and Intracellular Symbiosis, Orenburg, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2000 Jan-Feb(1):103-6.
The review deals with some theoretical and applied problems of the intraspecific diversity of pathogenic microorganisms. Special attention is given to the role of ecological factors in the formation of the phenotypic polymorphism of bacteria. The possibility of using the methods of mathematical analysis for the evaluation of the influence of the environment (ecotopes) on individual phenotypic characteristics of bacteria and their complex (bioprofile) is shown. The proposition on the bioprofile of microorganisms as a criterion of their ecological (ecotopic) marking is substantiated. The examples of using the data of the ecological marking of pathogenic bacteria in clinical epidemiology and ecological practice are presented.
本综述探讨了致病微生物种内多样性的一些理论和应用问题。特别关注了生态因素在细菌表型多态性形成中的作用。展示了使用数学分析方法评估环境（生态位）对细菌个体表型特征及其复合体（生物谱）影响的可能性。论证了将微生物生物谱作为其生态（生态位）标记标准的命题。列举了在临床流行病学和生态实践中使用致病细菌生态标记数据的实例。
