Liashenko I E, Gritsenko V A
Zh Mikrobiol Epidemiol Immunobiol. 1996 May-Jun(3):110-4.
The analysis of the penetrating and expressing capacity of the markers of bacterial persistence, adhesive capacity, antibiotic resistance and colicinogenicity in 254 E.coli strains of 7 groups, isolated from different ecotopes, including different environmental objects and bodies of healthy and sick children, revealed the specific character of their population bioprofiles, i.e. complexes of phenotypical signs of microorganisms. The results of the cluster analysis carried out with regard to the totality of data on E.coli bioprofiles made it possible to detect two clusters: the first cluster included pathogenic E.coli isolated from children with pathogenic processes, the second one included non-pathogenic E.coli isolated from healthy children and from aqueous objects. The levels of the information content of individual signs of microorganisms were determined and the use of E.coli bioprofiles for their epidemiological marking was substantiated.
对从不同生态位分离出的7组254株大肠杆菌进行分析，这些生态位包括不同的环境物体以及健康和患病儿童的身体，分析内容包括细菌持续性标志物的穿透和表达能力、黏附能力、抗生素抗性和产大肠杆菌素能力，结果揭示了它们群体生物谱的特异性，即微生物表型特征的复合体。根据大肠杆菌生物谱的全部数据进行聚类分析的结果，能够检测到两个聚类：第一个聚类包括从患有致病过程的儿童中分离出的致病性大肠杆菌，第二个聚类包括从健康儿童和水性物体中分离出的非致病性大肠杆菌。确定了微生物个体特征的信息含量水平，并证实了利用大肠杆菌生物谱进行流行病学标记的可行性。
