Loas G, Noisette C, Legrand A, Boyer P
University Department of Psychiatry, Pinel's Hospital, Amiens, France.
Schizophr Bull. 2000;26(2):495-506. doi: 10.1093/oxfordjournals.schbul.a033468.
This article explores the relationships among anhedonia, depression, and schizophrenic symptomatology in chronic schizophrenia. To explore these relationships, factor analysis methods were used to analyze the latent organization of the variables. The Fawcett Clark Pleasure Capacity Scale-Physical Pleasure (FCPCS-PP) and the abridged version of the Beck Depression Inventory (BDI) were completed by 150 subjects who met research diagnostic criteria for definite chronic schizophrenia. The schizophrenic symptomatology was rated using the Positive and Negative Syndrome Scale (PANSS). Two separate exploratory principal components analyses were completed, followed by varimax rotation. The first was made on the correlation matrix comprising items from both the FCPCS-PP and PANSS and yielded a five-factor solution with virtually no overlap of the significant factor loadings for the items from each scale. The second was made on the correlation matrix comprising items from both the FCPCS-PP and BDI and yielded a two-factor solution with virtually no overlap of the significant factor loadings for the items from each scale. Confirmatory factor analyses corresponding to the two exploratory factor analyses were done to examine the goodness of fit of the five-factor solution versus a four-factor solution and the two-factor solution versus a one-factor solution. The five-factor and the two-factor solutions yielded the best fit to the data relative to the other models tested. The findings support the view that part of anhedonia is a construct that is distinct and separate from depression and schizophrenic symptomatology in chronic schizophrenia.
本文探讨了慢性精神分裂症中快感缺失、抑郁和精神分裂症症状之间的关系。为了探究这些关系,采用了因子分析方法来分析变量的潜在结构。150名符合明确慢性精神分裂症研究诊断标准的受试者完成了福西特·克拉克愉悦能力量表-身体愉悦分量表(FCPCS-PP)和贝克抑郁量表简版(BDI)。使用阳性和阴性症状量表(PANSS)对精神分裂症症状进行评分。完成了两项独立的探索性主成分分析,随后进行了方差最大化旋转。第一次分析是对包含FCPCS-PP和PANSS项目的相关矩阵进行的,得出了一个五因素解决方案,每个量表项目的显著因子负荷几乎没有重叠。第二次分析是对包含FCPCS-PP和BDI项目的相关矩阵进行的,得出了一个两因素解决方案,每个量表项目的显著因子负荷几乎没有重叠。对应于两项探索性因子分析进行了验证性因子分析,以检验五因素解决方案与四因素解决方案以及两因素解决方案与单因素解决方案的拟合优度。相对于所测试的其他模型,五因素和两因素解决方案对数据的拟合效果最佳。这些发现支持了这样一种观点,即在慢性精神分裂症中,部分快感缺失是一种与抑郁和精神分裂症症状不同且相互独立的结构。