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慢性精神分裂症中的快感缺乏与阴性症状学

Anhedonia and negative symptomatology in chronic schizophrenia.

作者信息

Loas G, Boyer P, Legrand A

机构信息

Service Hospitalo-Universitaire, Hopital Pinel, Amiens, Paris, France.

出版信息

Compr Psychiatry. 1996 Jan-Feb;37(1):5-11. doi: 10.1016/s0010-440x(96)90043-7.

Abstract

The relationships between negative symptomatology and anhedonia have been studied on 61 subjects who had Research Diagnostic Criteria for chronic schizophrenia. Negative symptomatology was rated by the negative subscales of the Kay Positive and Negative Syndrome Scale (PANSS) and of the Brief Psychiatric Rating Scale (BPRS). Anhedonia was rated by the Physical Anhedonia Scale of Chapman (PAS), the Fawcett-Clark Pleasure Capacity Scale-Physical Pleasure (FCPCS-PP), and the social interest subscale (SIS) of the Nurse Observation Scale for Inpatients (NOSIE-30). Pearson correlations were calculated between negative and anhedonia scales. Schizophrenics were dichotomized first into negatives and positives using the composite score of the PANSS, and second into low and high negatives using the negative subscale of the PANSS. For each dichotomy, the corresponding subgroups were compared on anhedonia scales using Student's test. The results have shown no significant correlations between negative and anhedonia scales (PAS and FCPCS-PP). There were no significant differences concerning the PAS and the FCPCS-PP between negative and positive subgroups of schizophrenics and between low- and high-negative subgroups. Anhedonia is not a negative symptom. Our results confirm the reported studies on subjective experiences in schizophrenia. A search for more restricted forms of schizophrenia characterized by severe anhedonia is needed.

摘要

对61名符合慢性精神分裂症研究诊断标准的受试者,研究了阴性症状与快感缺失之间的关系。阴性症状通过凯氏阳性与阴性症状量表(PANSS)和简明精神病评定量表(BPRS)的阴性分量表进行评定。快感缺失通过查普曼身体快感缺失量表(PAS)、福西特 - 克拉克快感能力量表 - 身体快感(FCPCS - PP)以及住院患者护士观察量表(NOSIE - 30)的社会兴趣分量表(SIS)进行评定。计算阴性量表与快感缺失量表之间的皮尔逊相关性。首先使用PANSS的综合得分将精神分裂症患者分为阴性组和阳性组,其次使用PANSS的阴性分量表将其分为低阴性组和高阴性组。对于每组二分法,使用学生检验比较相应亚组在快感缺失量表上的得分。结果显示阴性量表与快感缺失量表(PAS和FCPCS - PP)之间无显著相关性。精神分裂症阴性和阳性亚组之间以及低阴性和高阴性亚组之间在PAS和FCPCS - PP方面无显著差异。快感缺失不是一种阴性症状。我们的结果证实了关于精神分裂症主观体验的已报道研究。需要寻找以严重快感缺失为特征的更局限形式的精神分裂症。

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