Grosse G, Lindner G, Matthies H J
Z Mikrosk Anat Forsch. 1976;90(3):499-506.
Cell- and explantcultures of the hippocampus of 18 days old fetal rats and explantcultures of the ganglion trigeminal of 9 days old chick embryos were cultivated in Maximow-chambers. Orotic acid, Sodiumorotate and methylglucaminorotate by concentrations of 10(-3)...10(-7) g/ml medium were added to the cultures. By concentrations of 10(-7) g/ml medium in the CNS-cultures and 10(-6) g/ml medium in the PNS-cultures is stimulated the nerve fiber growth and is increased the nerve fiber index. After three weeks in vitro is a higher number of neurons in the cultures compared to the controls.
将18日龄胎鼠海马的细胞培养物和外植体培养物以及9日龄鸡胚三叉神经节的外植体培养物在马克西莫夫培养室中培养。将浓度为10（-3）...10（-7）g/ml培养基的乳清酸、乳清酸钠和葡甲胺乳清酸盐添加到培养物中。在中枢神经系统培养物中浓度为10（-7）g/ml培养基以及在周围神经系统培养物中浓度为10（-6）g/ml培养基时，可刺激神经纤维生长并增加神经纤维指数。体外培养三周后，与对照组相比，培养物中的神经元数量更多。
