Hunt J, Gaston B
Division of Pediatric Pulmonary Medicine, The University of Virginia, Charlottesville 22951, USA.
J Pediatr. 2000 Jul;137(1):14-20. doi: 10.1067/mpd.2000.107526.
Markers for airway inflammation that can be measured noninvasively in expired air may be helpful in treating patients with asthma. For example, levels of nitric oxide are high in the breath of children with asthma exacerbations and decrease with anti-inflammatory therapy. Expired nitric oxide testing has now been standardized and may be useful for children with recurring wheezing that is diagnostically or therapeutically challenging. However, the results may be influenced by several biochemical and anatomic variables and must therefore be interpreted with caution.
可通过无创方式测量呼出气体中气道炎症的标志物，可能有助于治疗哮喘患者。例如，哮喘发作儿童呼出气体中的一氧化氮水平较高，且会随着抗炎治疗而降低。呼出一氧化氮检测现已标准化，对于反复喘息且诊断或治疗具有挑战性的儿童可能有用。然而，检测结果可能会受到多种生化和解剖学变量的影响，因此必须谨慎解读。
