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Infect Immun. 1975 Feb;11(2):334-6. doi: 10.1128/iai.11.2.334-336.1975.
2
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本文引用的文献

1
Enteropathogenicity of Escherichia coli. I. Evaluation of mouse intestinal loops.大肠杆菌的肠道致病性。I. 小鼠肠袢评估
Infect Immun. 1971 Oct;4(4):473-8. doi: 10.1128/iai.4.4.473-478.1971.
2
Enterotoxigenic Escherichia coli isolated from patients with severe cholera-like disease.从患有严重霍乱样疾病的患者中分离出的产肠毒素大肠杆菌。
J Infect Dis. 1971 Apr;123(4):378-85. doi: 10.1093/infdis/123.4.378.
3
Stimulation of steroidogenesis in tissue culture by enterotoxigenic Escherichia coli and its neutralization by specific antiserum.产肠毒素大肠杆菌对组织培养中类固醇生成的刺激作用及其被特异性抗血清的中和作用。
Infect Immun. 1974 Mar;9(3):500-5. doi: 10.1128/iai.9.3.500-505.1974.
4
Antitoxin responses to infections with enterotoxigenic Escherichia coli.针对产肠毒素大肠杆菌感染的抗毒素反应。
J Infect Dis. 1974 Mar;129(3):330-5. doi: 10.1093/infdis/129.3.330.
5
Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture.利用组织培养中的肾上腺细胞检测不耐热大肠杆菌肠毒素。
Science. 1974 Jan 25;183(4122):334-6. doi: 10.1126/science.183.4122.334.
6
Production of vascular permeability factor by enterotoxigenic Escherichia coli isolated from man.从人类分离出的产肠毒素大肠杆菌产生血管通透因子。
Infect Immun. 1973 Nov;8(5):725-30. doi: 10.1128/iai.8.5.725-730.1973.
7
Plasmid-associated enterotoxin production in a strain of Escherichia coli isolated from humans.从人类分离出的一株大肠杆菌中质粒相关肠毒素的产生
Infect Immun. 1972 Apr;5(4):622-4. doi: 10.1128/iai.5.4.622-624.1972.
8
Toxigenic Escherichia coli: a cause of infantile diarrhea in Chicago.产毒素大肠杆菌：芝加哥婴儿腹泻的一个病因。
N Engl J Med. 1972 Oct 19;287(16):791-5. doi: 10.1056/NEJM197210192871603.
9
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.利用幼鼠检测大肠杆菌肠毒素：在檀香山儿童腹泻研究中的应用
J Infect Dis. 1972 Apr;125(4):407-11. doi: 10.1093/infdis/125.4.407.
10
Induction of steroidogenesis in tissue culture by cholera enterotoxin.霍乱肠毒素在组织培养中诱导类固醇生成。
Nat New Biol. 1973 Jun 20;243(129):246-7. doi: 10.1038/newbio243246a0.

利用小型培养中的Y-1肾上腺细胞检测产肠毒素大肠杆菌

Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture.

作者信息

Sack D A, Sack R B

出版信息

Infect Immun. 1975 Feb;11(2):334-6. doi: 10.1128/iai.11.2.334-336.1975.

DOI:10.1128/iai.11.2.334-336.1975
PMID:1089601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC415066/
Abstract

A rapid, potentially clinically useful test for detection of enterotoxigenic Escherichia coli is described. Whole bacterial cultures of enterotoxigenic E. coli, when briefly exposed to Y1 adrenal cells in tissue miniculture, effect a rounding response in the tissue culture that can be discerned at 18 to 24 h. The tissue culture technique agreed with the rabbit ileal loop in all 58 enterotoxigenic and 52 non-enterotoxigenic E. coli strains tested.

摘要

本文描述了一种快速、可能具有临床实用价值的检测产肠毒素大肠杆菌的试验。产肠毒素大肠杆菌的全菌培养物在组织微量培养中短暂暴露于Y1肾上腺细胞时，可在18至24小时内使组织培养物出现变圆反应。在检测的58株产肠毒素大肠杆菌菌株和52株非产肠毒素大肠杆菌菌株中，该组织培养技术与兔回肠袢试验结果一致。