Mackenzie J, Ah-See K, Thakker N, Sloan P, Maran A G, Birch J, Macfarlane G J
Department of Otolaryngology, City Hospital, Edinburgh, UK.
Oral Oncol. 2000 Jul;36(4):387-9. doi: 10.1016/s1368-8375(00)00009-9.
The reasons for an increasing incidence of oral cancer, particularly amongst younger persons is unclear. It has been hypothesised either to be a result of an increase in exposure to known risk factors amongst certain groups in the community, or to be due to new aetiological agents. Prior to conducting large expensive population-based studies, it seems appropriate to conduct initial smaller-scale surveys to assess evidence for each of these two hypotheses. This survey of young persons with oral cancer suggest that most are exposed to traditional risk factors of tobacco smoking, drinking alcohol and a low consumption of fruit and vegetables.
口腔癌发病率上升的原因,尤其是在年轻人中发病率上升的原因尚不清楚。有人推测,这要么是社区中某些群体接触已知风险因素增加的结果,要么是由于新的致病因素。在开展大规模、昂贵的基于人群的研究之前,先进行初步的小规模调查以评估这两种假设的证据似乎是合适的。这项对年轻口腔癌患者的调查表明,大多数人都接触过吸烟、饮酒以及水果和蔬菜摄入量低等传统风险因素。