Mohrenweiser H, Neel J V, Mestriner M A, Salzano F M, Migliazza E, Simões A L, Yoshihara C M
Am J Phys Anthropol. 1979 Feb;50(2):237-46. doi: 10.1002/ajpa.1330500212.
Data are presented on electrophoretic variants of 25 polypeptides found in the blood serum and erythrocytes, in 812 individuals from three Amerindian tribes, the Pano, the Baniwa, and the Kanamari. Two "private polymorphisms" were encountered, of PEPB in the Pano and CAII in the Baniwa. A single example of a different PEPB variant was encountered in the Baniwa, and two possible examples of an unstable variant of HGB A2 in the Kanamari. In addition, the well-known A variant of ACP1, the Duarte variant of GALT, the 2 variant of Hp and the 2 variant of PGM1 occurred in polymorphic proportions in all three tribes, and the TFDChi variant was present as a polymorphism in the Baniwa. These data have recently been incorporated into a treatment which concludes that the eight electrophoretically-defined "private polymorphisms" thus far encountered in Amerindian tribes can be explained by a mutation pressure of 0.7 x 10(-5)/locus/generation on the assumption of neutrality of the phenotypes in question (Neel and Thompson, '78).
本文呈现了在来自三个美洲印第安部落（帕诺部落、巴尼瓦部落和卡纳马里部落）的812名个体的血清和红细胞中发现的25种多肽的电泳变体数据。发现了两种“私有多态性”，即帕诺部落中的PEPB和巴尼瓦部落中的CAII。在巴尼瓦部落中遇到了一个不同的PEPB变体的单一例子，在卡纳马里部落中遇到了两个可能的HGB A2不稳定变体的例子。此外，众所周知的ACP1的A变体、GALT的杜阿尔特变体、Hp的2变体和PGM1的2变体在所有三个部落中均以多态比例出现，并且TFDChi变体在巴尼瓦部落中以多态形式存在。这些数据最近被纳入了一项研究，该研究得出结论：假设所讨论的表型为中性，那么到目前为止在美洲印第安部落中遇到的8种电泳定义的“私有多态性”可以用0.7×10^(-5)/基因座/代的突变压力来解释（尼尔和汤普森，1978年）。
