Friberg J, Kjessler B
Am J Obstet Gynecol. 1975 Apr 1;121(7):987-90. doi: 10.1016/0002-9378(75)90923-0.
The relationship between the state of the germinal epithelium and the type and titer of circulating sperm-agglutinating antibodies has been investigated in a series of 59 azoospermic or occasionally cryptozoospermic men. The patients were grouped according to the condition of the germinal epithelium as observed from testicular biopsy specimens, as well as to type and titer of circulating sperm-agglutinating antibodies investigated by a previously described microagglutination technique. Evidence is presented to suggest that the presence of mature spermatozoa in the testicular structures may be a prerequisite for the spontaneous production of circulating sperm-agglutinating antibodies, at least of the head-to-tail (H-T) agglutinating type. Furthermore, these circulating H-T sperm-agglutinating antibodies, once they are formed, do not seem to interfere adversely with the germinal epithelium of the carrier.
在59例无精子症或偶发性隐匿精子症男性患者中，研究了生精上皮状态与循环精子凝集抗体类型及滴度之间的关系。根据睾丸活检标本观察到的生精上皮状况，以及通过先前描述的微凝集技术检测的循环精子凝集抗体的类型和滴度，对患者进行分组。有证据表明，睾丸结构中存在成熟精子可能是自发产生循环精子凝集抗体（至少是头尾（H-T）凝集型）的先决条件。此外，这些循环的H-T精子凝集抗体一旦形成，似乎不会对携带者的生精上皮产生不利影响。
