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先天性双侧输精管缺如的无精子症男性体内的循环精子凝集抗体。

Circulating sperm-agglutinating antibodies in azoospermic men with congenital bilateral absence of the vasa deferentia.

作者信息

Amelar R D, Dubin L, Schoenfeld C

出版信息

Fertil Steril. 1975 Mar;26(3):228-31. doi: 10.1016/s0015-0282(16)40991-x.

DOI:10.1016/s0015-0282(16)40991-x
PMID:1116619
Abstract

Congenital bilateral absence of the vasa deferentia has been found to be the cause for azoospermia in 101 patients who have been examined in our urologic practice since 1956. This represents approximately 2% of the 5112 patients seen during that time because of problems relating to infertility. Of these 101 men, 29 have had their sera tested for the presence of circulating sperm-agglutinating antibodies. The Shulman15 modification of the macroscopic gelatin sperm-agglutination test of Kibrick et al6 was used. None of these patients had had testicular biopsy. Significantly high titers (1:32 or greater) of antibodies were found in 18 (62.1%) men, low titers (1:16 or less) in five (17.2%), and no antibodies in six (20.7%).

摘要

自1956年以来,在我们泌尿外科诊治的患者中,已发现先天性双侧输精管缺如(CBAVD)是101例无精子症患者的病因。这约占同期因不育问题就诊的5112例患者的2%。在这101名男性中,29人检测了血清中循环精子凝集抗体的存在。采用了Kibrick等人6的宏观明胶精子凝集试验的Shulman15改良法。这些患者均未进行睾丸活检。18名(62.1%)男性发现抗体滴度显著升高(1:32或更高),5名(17.2%)为低滴度(1:16或更低),6名(20.7%)未发现抗体。

相似文献

1
Circulating sperm-agglutinating antibodies in azoospermic men with congenital bilateral absence of the vasa deferentia.先天性双侧输精管缺如的无精子症男性体内的循环精子凝集抗体。
Fertil Steril. 1975 Mar;26(3):228-31. doi: 10.1016/s0015-0282(16)40991-x.
2
Low fertility rate in vasovasostomized males and its possible immunologic mechanism.输精管吻合术后男性的低生育率及其可能的免疫机制。
Int J Fertil. 1975;20(3):183-91.
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Relationship of epididymal sperm antibodies to their in vitro fertilization capacity in men with congenital absence of the vas deferens.先天性输精管缺如男性附睾精子抗体与其体外受精能力的关系。
Fertil Steril. 1992 Nov;58(5):1006-10. doi: 10.1016/s0015-0282(16)55451-x.
4
Sperm antibodies in serum and semen in men with bilateral congenital absence of the vas deferens.双侧先天性输精管缺如男性血清和精液中的精子抗体
Arch Androl. 1982 Jun;8(4):301-5. doi: 10.3109/01485018208990214.
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Sperm-agglutinating antibodies and testicular morphology in fifty-nine men with azoospermia or cryptozoospermia.59例无精子症或隐匿性无精子症男性的精子凝集抗体与睾丸形态
Am J Obstet Gynecol. 1975 Apr 1;121(7):987-90. doi: 10.1016/0002-9378(75)90923-0.
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Testicular origin of immunobead-reacting antigens in human sperm.人类精子中免疫珠反应性抗原的睾丸起源
Fertil Steril. 1992 Jan;57(1):183-6. doi: 10.1016/s0015-0282(16)54798-0.
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Antispermatozoal antibodies in three men with infertility due to congenital aplasia of the vasa deferentia.三名因先天性输精管发育不全导致不育的男性体内的抗精子抗体
Am J Reprod Immunol Microbiol. 1988 Jun;17(2):48-52. doi: 10.1111/j.1600-0897.1988.tb00201.x.
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Low incidence of sperm antibodies in men with congenital absence of the vas deferens.先天性输精管缺如男性中精子抗体的低发生率。
Fertil Steril. 1989 Dec;52(6):1018-21. doi: 10.1016/s0015-0282(16)53168-9.
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Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen.输精管吻合术后未能受孕与精液中精子凝集素之间的关联。
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Spermagglutinating antibodies and beta-spermagglutinins in sera from infertile and fertile women.不育和可育女性血清中的精子凝集抗体和β-精子凝集素
Fertil Steril. 1979 May;31(5):496-502. doi: 10.1016/s0015-0282(16)43992-0.

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Potential causes and associated conditions with anti-sperm antibody production among infertile males: a systematic literature review.不育男性中抗精子抗体产生的潜在原因及相关情况:一项系统文献综述
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