Guyon F, Vaysseix G, Barillot E
GIS Infobiogen, Villejuif, France.
Pac Symp Biocomput. 2000:206-17. doi: 10.1142/9789814447331_0020.
The genome mapping projects now produce very dense maps with up to several thousands of markers per chromosome. Besides synteny plays a increasing role in mapping: enrichment of poor maps from the maps of close genomes (in terms of evolution) is a high-reward task. We propose a map viewer adapted to this situation: MappetShow gives a clear view of very dense maps and compares efficiently several maps. MappetShow is based on non-linear viewing and is written in Java. A map description language isolates the software from the data sources. This software was easily used on data coming from as different sources as an Object Request Broker, an Object-Oriented Database, or a flat data stream. MappetShow can be browsed at the URL http:¿www.infobiogen.fr/services/Mappet. More generally we discuss how to use the non-linear viewing concept in molecular biology data visualization.
目前的基因组图谱绘制项目能够生成非常密集的图谱,每条染色体上有多达数千个标记。此外,同线性在图谱绘制中发挥着越来越重要的作用:从亲缘关系较近的基因组(从进化角度而言)的图谱中丰富较差的图谱是一项高回报的任务。我们提出了一种适用于这种情况的图谱查看器:MappetShow能够清晰地展示非常密集的图谱,并能有效地比较多个图谱。MappetShow基于非线性查看方式,用Java编写。一种图谱描述语言使该软件与数据源隔离开来。该软件可以很容易地用于来自诸如对象请求代理、面向对象数据库或平面数据流等不同来源的数据。可以通过网址http://www.infobiogen.fr/services/Mappet浏览MappetShow。更广泛地说,我们讨论了如何在分子生物学数据可视化中使用非线性查看概念。