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一种整合了甘蓝型油菜和拟南芥遗传图谱的比较图谱查看器。

A comparative map viewer integrating genetic maps for Brassica and Arabidopsis.

作者信息

Lim Geraldine A C, Jewell Erica G, Li Xi, Erwin Timothy A, Love Christopher, Batley Jacqueline, Spangenberg German, Edwards David

机构信息

Plant Biotechnology Centre, Primary Industries Research Victoria, Department of Primary Industries, Victorian AgriBiosciences Centre, Bundoora, Victoria, Australia.

出版信息

BMC Plant Biol. 2007 Jul 24;7:40. doi: 10.1186/1471-2229-7-40.

Abstract

BACKGROUND

Molecular genetic maps provide a means to link heritable traits with underlying genome sequence variation. Several genetic maps have been constructed for Brassica species, yet to date, there has been no simple means to compare this information or to associate mapped traits with the genome sequence of the related model plant, Arabidopsis.

DESCRIPTION

We have developed a comparative genetic map database for the viewing, comparison and analysis of Brassica and Arabidopsis genetic, physical and trait map information. This web-based tool allows users to view and compare genetic and physical maps, search for traits and markers, and compare genetic linkage groups within and between the amphidiploid and diploid Brassica genomes. The inclusion of Arabidopsis data enables comparison between Brassica maps that share no common markers. Analysis of conserved syntenic blocks between Arabidopsis and collated Brassica genetic maps validates the application of this system. This tool is freely available over the internet on http://bioinformatics.pbcbasc.latrobe.edu.au/cmap.

CONCLUSION

This database enables users to interrogate the relationship between Brassica genetic maps and the sequenced genome of A. thaliana, permitting the comparison of genetic linkage groups and mapped traits and the rapid identification of candidate genes.

摘要

背景

分子遗传图谱提供了一种将可遗传性状与潜在基因组序列变异联系起来的方法。已经为芸苔属物种构建了几个遗传图谱,但迄今为止,还没有简单的方法来比较这些信息或将定位的性状与相关模式植物拟南芥的基因组序列相关联。

描述

我们开发了一个比较遗传图谱数据库,用于查看、比较和分析芸苔属和拟南芥的遗传、物理和性状图谱信息。这个基于网络的工具允许用户查看和比较遗传图谱和物理图谱,搜索性状和标记,并比较双二倍体和二倍体芸苔属基因组内部和之间的遗传连锁群。纳入拟南芥数据能够对没有共同标记的芸苔属图谱进行比较。对拟南芥和整理后的芸苔属遗传图谱之间保守的共线区域进行分析,验证了该系统的实用性。该工具可通过互联网在http://bioinformatics.pbcbasc.latrobe.edu.au/cmap上免费获取。

结论

该数据库使用户能够探究芸苔属遗传图谱与拟南芥测序基因组之间的关系,允许比较遗传连锁群和定位的性状,并快速鉴定候选基因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd1e/1940001/10afa3080ff6/1471-2229-7-40-1.jpg

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