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抗核抗体。II. 红斑狼疮中核免疫荧光模式的预后意义。

Antinuclear antibodies. II. The prognostic significance of nuclear immunofluorescent patterns in lupus erythematosus.

作者信息

Burnham T K

出版信息

Arch Dermatol. 1975 Feb;111(2):203-7. doi: 10.1001/archderm.111.2.203.

DOI:10.1001/archderm.111.2.203
PMID:1090261
Abstract

Nuclear immunofluorescent patterns in lupus erythematosus (LE) were correlated with the clinical picture. Patterns were classified into three groups of prognostic significance: (1) Poor-Shrunken peripheral fluorescence was found in patients with severe systemic lupus erythematosus (SLE), 60% demonstrating renal involvement. (2) Intermediate-This included the peripheral and therapy patterns, associated with 33% renal involvement in patients with SLE. (3) Good-Large and small speckle-like threads were seen in cases of very benign LE.

摘要

红斑狼疮(LE)的核免疫荧光模式与临床表现相关。这些模式被分为具有预后意义的三组:(1)差——在重症系统性红斑狼疮(SLE)患者中发现外周荧光收缩,60%有肾脏受累表现。(2)中——这包括外周型和治疗型模式,SLE患者中有33%出现肾脏受累。(3)好——在病情非常良性的LE病例中可见大小不一的斑点状细丝。

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引用本文的文献

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[Antinuclear antibodies in diagnosis of rheumatic diseases (author's transl)].抗核抗体在风湿性疾病诊断中的应用(作者译)
Klin Wochenschr. 1981 Mar 16;59(6):287-96. doi: 10.1007/BF01478208.
2
Application of immunological principles in dermatology.免疫学原理在皮肤病学中的应用。
J Natl Med Assoc. 1975 Nov;67(6):423-7, 454.
3
Immunologic findings, thrombocytopenia and disease activity in lupus nephritis.狼疮性肾炎的免疫学发现、血小板减少症与疾病活动度
Can Med Assoc J. 1978 Jun 10;118(11):1391-5.