Bowszyc J
Arch Dermatol Forsch. 1975;251(3):227-34.
Two modifications of macrophage migration inhibition test, one of George and Vaughan and the other one of Svejcar, were performed on a total of 78 cases of untreated syphilis at various stages. As specific antigens were used: Treponema Pallidum ultrasonate and cardiolipin. Inhibition of migration was observed in 87 percent patients with primary syphillis and in all patients with late and late congenital syphilis. After improving and standardisation of the technique of Treponema Pallidum antigen-the migration inhibition test may be recommended as a specific in vitro-test for detection of cell mediated immunity in syphilis.
对总共78例处于不同阶段的未经治疗的梅毒患者进行了两种改良的巨噬细胞游走抑制试验，一种是乔治和沃恩法，另一种是斯韦卡尔法。使用的特异性抗原为：梅毒螺旋体超声提取物和心磷脂。在一期梅毒患者中，87%观察到游走受到抑制，在晚期梅毒和晚期先天性梅毒患者中，所有患者均观察到游走受到抑制。在改进并标准化梅毒螺旋体抗原技术后，游走抑制试验可作为检测梅毒细胞介导免疫的一种特异性体外试验。
