Noly J C, Sepetjan M, Monier J C
Nouv Presse Med. 1979 Mar 24;8(14):1141-2.
During rabbit experimental syphilis a suspension of Treponema pallidum (TP) was used as antigen. The evolution of anti TP antibodies was followed up to the fifteenth month, the antibody titer was maximum at month seven. A stimulation of leukocytes migration test was observed up to the sixth month then a significant inhibition appeared (chi square test) which persists after the ninth month. Hence the possibility was discussed that some form of cellular immunity appears secondary while immune response was mostly of humoral type at the beginning of the disease.
在兔实验性梅毒中,使用梅毒螺旋体(TP)悬液作为抗原。对抗TP抗体的演变进行了长达15个月的跟踪,抗体效价在第7个月时最高。在第6个月之前观察到白细胞迁移试验受到刺激,然后出现显著抑制(卡方检验),这种抑制在第9个月后持续存在。因此,有人讨论了在疾病初期免疫反应主要是体液免疫类型时,某种形式的细胞免疫可能是继发性出现的可能性。