Rose C H, Rowe T F, Cox S M, Malinak L R
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA.
J Matern Fetal Med. 2000 Mar-Apr;9(2):150-2. doi: 10.1002/(SICI)1520-6661(200003/04)9:2<150::AID-MFM12>3.0.CO;2-K.
Congenital bladder exstrophy affects 1 in 125,000 to 250,000 females. Consisting of absence of the anterior abdominal wall with exposure of the ureteral orifices, failure of pubic symphysis fusion, and deficient anterior pelvic diaphragm musculature, bladder exstrophy is frequently associated with genital prolapse. Pregnancy may be complicated by recurrent urinary tract infections, preterm labor, mild procidentia, and malpresentation. Due to the rarity of the condition, there is a corresponding scarcity of obstetric literature regarding management during pregnancy. We report the case of a young woman with surgically repaired bladder exstrophy who developed genital prolapse. The uterus was suspended using a sacral colpopexy utilizing a Gore-Tex graft. Subsequently, the patient became pregnant and delivered a healthy male infant at 35 weeks' gestation via cesarean section (without recurrence of the genital prolapse postpartum). Sacral colpopexy to correct genital prolapse associated with bladder exstrophy may preserve fertility in young patients.
先天性膀胱外翻在12.5万至25万女性中出现1例。膀胱外翻表现为前腹壁缺失,输尿管口暴露,耻骨联合融合失败以及骨盆前膈肌肉组织发育不全,常伴有生殖器脱垂。妊娠可能并发反复尿路感染、早产、轻度子宫脱垂和胎位异常。由于该病罕见,关于孕期管理的产科文献相应匮乏。我们报告1例接受膀胱外翻手术修复的年轻女性发生生殖器脱垂的病例。使用戈尔泰克斯移植物通过骶骨阴道固定术悬吊子宫。随后,该患者怀孕,并在妊娠35周时通过剖宫产分娩出一名健康男婴(产后生殖器脱垂未复发)。采用骶骨阴道固定术纠正与膀胱外翻相关的生殖器脱垂可能会保留年轻患者的生育能力。